Confocal Laser Scanning Microscopy (CLSM) is a specialized imaging technique that allows for the visualization of structures within biological samples in three dimensions. It utilizes lasers to scan the sample at different depths, creating a series of images that can be reconstructed into a 3D image. CLSM has a high resolution and can be used for a variety of applications, including studying the morphology and function of cells, tissues, and organs. It requires specialized equipment and training to use effectively.