Biodistribution is a method of tracking where compounds of interest travel in an experimental animal or human subject. For example, in the development of new compounds for PET scanning, a radioactive isotope is chemically joined with a peptide. This particular class of isotopes emits positrons. When ejected from the nucleus, positrons encounter an electron, and undergo annihilation which produces two gamma rays travelling in opposite directions. These gamma rays can be measured, and when compared to a standard, quantified.Read more on Wikipedia
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