Django is a high-level, open-source web framework written in Python. It is designed to help developers easily build and maintain complex web applications by providing a set of powerful tools and features, such as a built-in ORM for database management, a templating system for creating dynamic web pages, and a robust security framework for protecting against common web vulnerabilities. Django is widely used in the development of popular websites and applications, including Instagram, Pinterest, and Mozilla. A good understanding of Django is a valuable skill for web developers working with Python.