Tissue Culture Infective Dose (TCID50) Assays
The Tissue Culture Infective Dose (TCID50) assay is a specialized technique used to determine the concentration of infectious particles in a biological sample. It involves culturing cells and then inoculating them with the sample to be tested. The endpoint of the assay is the dilution at which 50% of the cells are infected, which provides a measure of the concentration of infectious particles in the sample. This assay is commonly used in virology and requires specialized skills in tissue culture and virology.
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